Probiotic products are popular and pretty much ubiquitous nowadays.
Probiotics, which are live microorganisms with beneficial effects, are used to
treat and prevent human illnesses. A variety of probiotics are available, and
each has different properties. However, in order for probiotics to perform
their functions, they need to survive in the human gastrointestinal environment.
These microorganisms can display antimicrobial properties and boost the immune
system. Probiotics are now studied as a way to counteract persistent
respiratory infections. This study tested different probiotics to determine
immunomodulatory properties and identify which one reduces influenza infection symptoms
the most. Preliminary experiments were conducted to select candidates for
animal testing. The first stage revealed that 44% of probiotics showed growth
delay and gastrointestinal resistance. Further analysis of the three selected microorganisms concluded in the selection of the probiotic labelled CNRZ1197
as the most efficient in protecting against infections. Future research involves
a deeper study of this probiotic targeted toward medicinal applications.
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| Figure from Kechaou et al. (2013) shows the viral score of different probiotics after infection treatment. The lowest score detected belongs to the chosen probiotic, CNRZ1997. |
Original article: Kechaou N, Chain F, Gratadoux JJ, Blugeon S, Bertho N, Chevalier C, et al. (2013). Identification of one novel candidate probiotic Lactobacillus plantarum strain active against influenza virus infection in mice by a large-scale screening. Appl Environ Microbiol 79: 1491-1499.
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