Amoxicillin Resistance During Composting
by: Diana Tarver
Figure 1. Dynamic changes of (A)Amoxicillin-resistant bacteria and (B) Amoxicillin-resistant bacteria during composting (days) and how many bacteria were counted. (CK) is the control group, regular compost bacteria with no amoxicillin.
Amoxicillin is the most used beta-lactam antibiotic as it is used for both humans and livestock. This changes their microbiome which in turn, affects the manure microbiome with possible antibiotic-resistant bacteria. Studying the environmental and human health risk of antibiotic resistant bacteria being transferred so close to our food sources particularly composting, we love using compost even for our backyard gardens, buying manure can be an important part of the microbiome of compost but as stated antibiotics change manure microbiome. Such is that a study carried out by Ning Liu and colleagues looked into the environmental drivers and interactions of bacteria in compost. Samples of pig manure were taken from a pig farm in Shunyi District with the assurance that no antibiotics were used from sampled pigs. Amoxicillin was mixed in by researchers along with a control group with no antibiotic. Their results found good news in that the exposure to composting reduced the availability of heavy metals and amoxicillin reducing the pressure for bacteria to need resistance to antibiotics. Figure 1. This data shows a drastic drop in amoxicillin in both A and B charts, the control group (CK) even starting off with low numbers stabilized the amoxicillin resistant bacteria. This goes to show microbiomes are incredibly powerful by using organic waste products we could promote resource recovery in agriculture.
Original article:
Liu, N., Li, G., Su, Y., Zhao, Y., Ma, J., & Huang, G. (2023). Environmental drivers and interaction mechanisms of heavy metal and antibiotic resistome exposed to amoxicillin during aerobic composting. Frontiers in Microbiology, 13. https://doi.org/10.3389/fmicb.2022.1079114
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