Wednesday, October 25, 2017

Location. Location. Location. Not Just For Real Estate.

By: Jackeline Santillano



Description of the living environments and how they were set up with what they will contain. Figure taken from Zhou et al. 2016.


Everyone knows that different environments will have a different microbial community. Who knew that it could even affect the microbes in our guts as well. This study uses a common model organism we all know as mice to be observed under three environments under different conditions. The first being a pathogen-free environment, the second being a household environment and the third being a farm environment. Any other variable was controlled for all three groups in the study. By using a high-throughput sequence of the 16S rRNA gene, it was found that all three groups had their own specific community of gut microbes. It was concluded that the different exposures in their environments would enhance diversity in the microbial community and increase born resistance of mice to pathogens. This is important because mice are model organisms for us humans and this will help understand how different environments affect even our gut microbial community.

Zhou, D., Zhang, H., Bai, Z., Zhang, A., Bai, F., Luo, X., Hou, Y., Ding, X., Sun, B., Sun, X., Ma, N., Wang, C., Dai, X. and Lu, Z. (2016), Exposure to soil, house dust and decaying plants increases gut microbial diversity and decreases serum immunoglobulin E levels in BALB/c mice. Environ Microbiol, 18: 1326–1337. doi:10.1111/1462-2920.12895



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